NF κB P105/P50 Mouse Monoclonal Antibody(4D11)
Catalog NO.：BE4057
Applications ：WB
Reactivity ：H, M
| 货号 | 规格 | 品牌 | 库存 | 价格 | 数量 | 操作 |
|---|---|---|---|---|---|---|
| BE4057-100 | 100ul | EASYBIO |
|
Nuclear factor kappa B subunit 1(NFKB1) Homo sapiens This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth.
| Product Name: | NF κB P105/P50 Mouse Monoclonal Antibody(4D11) |
|---|---|
| Isotype: | IgG1 |
| Storage Buffer : | 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
| Storage instructions: | -20°C. Do not aliquot the antibody |
| Recommended dilutions: | WB: 1:500-1,000 |
| Optimal dilutions should be determined by the end user. | |
| Specificity： | The NF κB P105/P50 Mouse Monoclonal antibody can recognize recombinant and endogenous NF κB P105/P50 proteins. |
| Alternative Names： | NFKB1, nuclear factor nf-kappa-b p105,DNA-binding factor KBF1 |
| Form: | Liquid |
| Reactivity: | H, M |
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